WikiFox

Terizidone



Terizidone is a drug used in the treatment of tuberculosis.[1] Terizidone is mainly used in multi-drug-resistant tuberculosis (MDR-TB) in conjunction with other second-line drugs. It is a derivate of cycloserine and it is bacteriostatic.[2]

Terizidone
Terizidone.svg
Clinical data
Other names4-[({4-[N-(3-oxo-1,2-oxazolidin-4-yl)carboximidoyl]phenyl}methylidene)amino]-1,2-oxazolidin-3-one
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • C
ATC code
Identifiers
  • 4,4'-{1,4-Phenylenebis[(E)methylylidene
    (E)azanylylidene]}bis(1,2-oxazolidin-3-one)
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.042.882 Edit this at Wikidata
Chemical and physical data
FormulaC14H14N4O4
Molar mass302.290 g·mol−1
3D model (JSmol)
  • O=C3NOCC3/N=C/c2ccc(/C=N/C1C(=O)NOC1)cc2
  • InChI=1S/C14H14N4O4/c19-13-11(7-21-17-13)15-5-9-1-2-10(4-3-9)6-16-12-8-22-18-14(12)20/h1-6,11-12H,7-8H2,(H,17,19)(H,18,20)/b15-5+,16-6+ check
  • Key:ODKYYBOHSVLGNU-IAGONARPSA-N check
 ☒check (what is this?)  (verify)

References

  1. ^ Galietti F, Giorgis GE, Oliaro A, Boaro D, Ardizzi A, Barberis S, Massaglia GM (1991). "[Tolerability to terizidone (TZ) in the treatment of pulmonary tuberculosis in dialyzed patients]". Minerva Medica. 82 (7–8): 477–81. PMID 1922892 .
  2. ^ Rossiter D (2012). South African Medicines Formulary. Cape Town, South Africa: Health and Medical Publishing Group of the South African Medical Association. pp. 323–325. ISBN 978-1-875098-28-6.




Source


Information as of: 11.08.2021 10:19:53 CEST

Source: Wikipedia (Authors [History])    License of the text: CC-BY-SA-3.0. Creators and licenses of the individual images and media can either be found in the caption or can be displayed by clicking on the image.

Changes: Design elements were rewritten. Wikipedia specific links (like "Redlink", "Edit-Links"), maps, niavgation boxes were removed. Also some templates. Icons have been replaced by other icons or removed. External links have received an additional icon.

Please note: Because the given content is automatically taken from Wikipedia at the given point of time, a manual verification was and is not possible. Therefore WikiFox.org does not guarantee the accuracy and actuality of the acquired content. If there is an Information which is wrong at the moment or has an inaccurate display please feel free to contact us: email.
See also: Legal Notice & Privacy policy.